Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours

A targetable epigenetic node of myeloid progenitor dysregulation that sustains immunoregulatory mo-macs in the…

Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling

Highlights•Astrocyte processes reduce contact with synapses before synapse removal by microglia•Microglia-de…

Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

Highlights•Erythroblast island (EBI) macrophages are recruited to the bone metastatic niche•EBI macrophages …

Septal LYVE1+ macrophages control adipocyte stem cell adipogenic potential

In addition to their role in host defense, macrophages contribute to the development and remodeling of tissues…

Therapeutic genetic restoration through allogeneic brain microglia replacement

AbstractAs tissue resident macrophages of the central nervous system (CNS) parenchyma, microglia perform diver…